Neurons information
- Brain is a single organinternal structure and organization are quite complex.
- Contains about 1011 neurons,
- Mature neurons do not have the ability to go under Mitosis
- The "normal" loss of neurons has been estimated to be about 103 per hour, in 75 years (660,000 hours), a loss of only 0.66 percent of the total number of neurons present at birth.
- People of advanced age
- less brain substance than their younger counterparts.
- brain shrinkage with age
- Environmental factors: accidents, drug use, can increase the rate of either cell shrinkage or cell loss.
Basic structural and functional units of the nervous
system. They cannot divide by mitosis. The fully differentiated, post-mitotic
cells cannot be replaced during the lifetime of the organism. As neurons die in
the course of normal aging, they cannot be replaced. Therefore, the maximum
number of neurons exists near the time of birth.
Neurons respond to physical and chemical
stimuli.These cells are able to produce and conduct electrochemical impulses.
Electrical impulse move from one cell to another cell by the release chemical
regulators.
Cell body (perikaryon):
·
“Nutrition center.”
·
Cell bodies within CNS clustered into
nuclei,
and in PNS in ganglia.
and in PNS in ganglia.
·
Dendrites:
–
Provide receptive area.
–
Transmit electrical impulses to cell
body.
·
Axon:
–
Conducts impulses away from cell body.
–
Each neuron usually contains an axon
·
Synapses
–
cell body of another neuron (axo-somatic
synapses),
–
contact dendrites (axo-dendritic
synapses).
–
one cell's axon and another cell's axon
(axo-axonic, or presynaptic, synapses).
Neurons are Excitable cells. They vary considerably
in size and shape, Important biochemical and physiological properties are
common.The dendrites are the short processes of the cell body. They conduct the
nerve impulse toward the cell body.Axon is the largest process of the cell
body. An axon conducts impulses away from the cell body. The majority of axons
within the CNS, are only a centimeter or two in length. The dendrites and axons
are often referred to as nerve fibers. Within the CNS, most axons make
functional connections with other neurons at junctions called synapses.
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