Saturday, January 4, 2014

Accessory organs

•         Produce and store digestive chemicals
•         Food does not pass through these

•         Liver - Produces bile; Stores glucose as glycogen & releases glucose into blood stream
•         Gallbladder - Stores bile, Squirts bile into small intestine when fat arrives
•         Pancreas - Makes enzymes. Empties into small intestine
•         Pancreatic juice: enzymes, bicarbonate
•         Insulin and glucagon secreted directly into blood
•         Insulin: Enables cells to use glucose (glucose enters cells) & promotes formation of glycogen in liver     
•         Glucagons: Signals to the liver to convert glycogen into glucose & release it into the bloodstream

Liver Functions

    1. Forms bile (assists fat digestion), rids body of excess cholesterol and blood's respiratory pigments
    2. Controls amino acid levels in the blood; converts potentially toxic ammonia to urea
    3. Controls glucose level in blood; major reservoir for glycogen
    4. Removes hormones that served their functions from blood
    5. Removes ingested toxins, such as alcohol, from blood
    6. Breaks down worn-out and dead red blood cells, and stores iron
    7. Stores some vitamins                

Pancreas

•         Lies between the stomach and duodenum
•         It secretes pancreatic juice which passes to the duodenum to help in digestion
–        Amylase – for digesting starch
–        Protease – protein
–        Lipase – fat

Stomach Disorders

Stomach Disorders

Gastroesophageal Refiux In some people, the gastroesophageal sphincter at the entrance to the stomach does not close properly or opens when it should not. The result is gastroesophageal reflux. Acidic chyme splashes back into the esophagus, causing a burning pain commonly called heartburn or acid indigestion. Occasional acid reflux can be treated with over-the-counter antacids, but a chronic problem should be discussed with a doctor. Repeated exposure to acid can damage the tissue of the esophagus and raise the risk of esophageal cancer.
Stomach Ulcers When something disrupts the stomach's protective mucus layer, gastric fluid and enzymes can erode the stomach lining, causing an ulcer. Most ulcers occur after an acid-loving species of bacteria (Helicobacter pylori) makes its way through gastric mucus and infects cells of the stomach lining. H. pylori releases chemicals that increase gastrin secretion, thus making the stomach more acid. The extra acidity stresses cells of the stomach lining so the infection spreads more easily. Antibiotics halt the infection and allow healing to occur.
Continual use of nonsteroidal anti-inflammatory drugs such as ibuprofen or aspirin can also cause a stomach ulcer. These drugs interfere with chemical signals that maintain the health of the stomach lining.

Disorders That Affect Digestion in the Small Intestine

Lactose Intolerance To be able to digest lactose, a person must have functional lactase at the surface of their brush border cells. In many people, including most Asians and African Americans, expression of the gene for lactase declines in adulthood. As a result, lactose is not broken down in the small intestine. When lactose enters the large intestine, resident bacteria break it down in reactions that produce hydrogen gas as a by-product. The result is flatulence, a feeling of bloating, and cramps.

Disorders That Affect Digestion in the Large Intestine

Appendicitis—an inflammation of the appendix— requires prompt treatment. It often occurs after a bit of feces lodges in the appendix and infection sets in. Removing an inflamed appendix prevents it from bursting and releasing bacteria into the abdominal cavity. Such a rupture could cause a lifc-threatcninc infection.

Friday, January 3, 2014

Human Nutritional Requirements

Energy-Rich Carbohydrates

Fresh fruits, whole grains, and vegetables—especially legumes such as peas and beans—provide abundant complex carbohydrates . The body breaks the starch in these foods into glucose, your primary source of energy. These foods also provide essential vitamins and fiber. Eating foods high in soluble fiber helps lower one's cholesterol level and may reduce the risk of heart disease. A diet high in insoluble fiber helps prevent constipation.
Foods rich in processed carbohydrates such as white flour, refined sugar, and corn syrup are sometimes said to be lull of "empty calories/' This is a way of saying that these foods provide little in the way of vitamins or fiber.
You may have noticed breads and other grain-based foods labeled as "gluten-free." Gluten is a protein found in  wheat and many other grains. An estimated 1 percent of the population has a genetic disorder called celiac disease, in which gluten causes an autoimmune reaction that harms the small intestine's villi. Celiac disease is treated by eliminating gluten from the diet.

Good Fat, Bad Fat

Your body uses lipids to build cell membranes, as energy stores, and as a reservoir for fat-soluble vitamins.
Linoleic acid and alpha-linolenic acid arc essential fatty acids, meaning the human body needs them but cannot make them, so they are required in the diet. Both are polyunsaturated fats; their long carbon tails include two or more double bonds. Unsaturated fats are liquid at room temperature.
We divide the polyunsaturated fatty acids into two categories: omega-3 fatly acids and omega-6 fatty acids. Omega-3 fatty acids, the main fat in oily fish such as sar dines, seem to have special health benefits. Studies suggest that a diet high in omega-3 fatty acids can reduce the risk of cardiovascular disease, lessen the inflammation associated with rheumatoid arthritis, and help diabetics control their blood glucose. Oleic acid, the main fat in olive oil. may also have health benefits. It is monounsaturated, which means its carbon tails have only one double bond. A diet in which olive oil is substituted for saturated fats helps prevent heart disease.
Dairy products and meats are rich in saturated fats and cholesterol. Overindulging in these foods increases one's risk for heart disease, stroke, and some cancers.
Trans fatty acids, or trans fats, are manufactured from vegetable oils. However, they have a molecular structure that makes them even worse for the heart than saturated fats. All food labels are now required to show the amounts of trans fats, saturated fats, and cholesterol per serving.

Body-Building Proteins

Amino acids are building blocks of proteins. Your cells can make some amino acids but you must get eight essential amino acids from food.Most proteins in meat are "complete," meaning their amino acid ratios match a human's nutritional needs. By contrast, most plant proteins are "incomplete," meaning they lack one or more amino acids essential for the human diet.
The American Dietetic Association states that, with careful planning, a vegetarian diet can provide all essential nutrients for people in any stage of life. To obtain all the required amino acids from plant sources alone, one must combine foods so that the amino acids missing from one component are present in some oth ers. As an example, rice and beans together provide all necessary amino acids, but rice alone or beans alone do not. You do not have to eat the two complementary foods at the same meal, but both should be consumed within a 24-hour period.

Vitamins and Minerals

Vitamins are organic substances that are essential in very small amounts; no other substance can carry out their metabolic functions. At a minimum, human cells require the thirteen vitamins. Minerals are inorganic substances that are essential for growth and survival because no other substance can serve their metabolic functions. Red blood cells require iron to make oxygen-transporting hemoglobin. Iodine is essential for development of a healthy nervous system and to make thyroid hormone.

What is a Healthy Weight?

 How reliable is BMI as an indicator of body fatness?

The correlation between the BMI number and body fatness is fairly strong, however the correlation varies by sex, race, and age
  • ·         At the same BMI, women tend to have more body fat than men.
  • ·         At the same BMI, older people, on average, tend to have more body fat than younger adults.
  • ·         Highly trained athletes may have a high BMI because of increased muscularity rather than increased body fatness.
BMI is only one factor related to risk for disease, For assessing someone's likelihood of developing overweight- or obesity-related diseases. The individual's waist circumference (because abdominal fat is a predictor of risk for obesity-related diseases). Other risk factors the individual has for diseases and conditions associated with obesity (for example, high blood pressure or physical inactivity).

How to calculate how many kilocalories you need

1.      Multiply the weight (in pounds) ,
  •       by 10 if you are not active physically,
  •       by 15 if you are moderately active, and
  •       by 20 if you are highly active
2.      Subtract one of the following amounts from the multiplication result


For example, if you are 25 years old, are highly active, and weigh 120 pounds, you will require 120 X 20 = 2,400 kilocalories daily to maintain weight. If you want to gain weight you will require more; to lose, you will require less. The amount is only a rough estimate.
Other factors, such as height, must be considered. A person 5 feet, 2 inches tall and active does not require as much energy as an active 6-footer whose body weight is the same.

Calorie value of food :

   a) Carbohydrate  -   4.4 k.cal/g.
   b) Fat                   -   9.3 k.cal/g. 
 c) Protein             -   4.0 k.cal/g.

The nervous system is an electrochemical communication


1. It receives sensory messages from the external environment.
2. It organizes information and integrates it with already stored information.
3. It uses integrated information to send out messages to muscles and glands, producing organized movement and secretions.
4. It provides the basis for conscious experience.